Friday, May 30, 2008

May 29



I wanted to share some pictures with you that I took during Doug's stem cell infusion. I took more pictures than my blog allows for one posting. I hope pictures speak louder than my words to describe this awesome event in our family's life.

The medical technologist came to the clinic with the cells in a caldren of refrigerated nitrogen. The cells collected were spun in the blood bank's lab and 25 cc's of stem cells were put into each of two bags. Each bag also contained 25 cc of DMSO, a preservative, which does not harm the patient but leaches out of their bodies producing an oder which to me smelled like cream corn that you get in a can.

Since the day of collection Doug's cells have been kept frozen at -196 degrees celcius. The med tech, Natalie. who brought the cells works for the Carter Blood Bank. They will store 1/2 of the cells collected from Doug should Doug ever have need for them in the future.

Natalie's undergraduate degree is in clinical lab science. She is certified by the American Society of Clinical Pathology to do this specialized work. What we found interesting is that she is a cancer survivor who has been cancer-free for 14 years. I'd guess her to be in her early 30's.

The two chemo nurses and Natalie trippled checked the label on the packaging to be sure the stem cells were Doug's and going back into the correct patient. Natalie read to Debbie then Debbie to Fatima.

In the picture above you can see that each bag of cells is contained in a protective metal case. They come frozen flat. Then the bag of cells is placed in a machine that Natlie brings with her called (in laypeople terms) " the warming bath". When the stem cells come up to body temperature the bag of cells is ready for infusion. The team works together rapidly at that point.













The "blessing" of the cells took place (see the other May 29 posting). The first bag was hung on the pole with the other hydrading fluids that Doug received prior to the arrival of the cells and were connected to Doug's central line. I called it his new life link. Meanwhile Natalie is warming the second bag of cells.

One of the chemo nurses monitored Doug's vitals the entire time while the other nurse monitored the rate of flow of the cells into Doug's central line. Because Doug's collection was so successful with so many stem sells per micro lieter he only had two bags of stem cells whereas others frequently have more than two even as many as eight bags.

Each bag took 20 minutes to drain so that in 40 minutes Doug's happy cells were using their God-given instinct to find their way back into Doug's bone marrow. Natalie explained that the cells have receptors on the outside and when returned know right where to go. They set up shop in the bone marrow and within a couple of days they start dividing. Meanwhile Doug will feel weak and fatigured.

Doug was comfortable during the entire process and said he felt nothing. I can't help but tell you I have a picture of him talking on his cell phone to a pastor who called him just before the action started. When I heard Doug say "How can I be of help to you?" I wondered if the pastor had any idea what Doug looked like from where I was sitting.

When the infusion was complete and Doug was unhooked he stood up and walked with me to the car and rode with me to the pharmacy to pick up a perscription. I can't find words to describe what that felt like to both of us.

We go to the clinic every day now. We have to be real careful of infection/fever until his immune system kicks back in. Friday and Saturday he will have blood transfusions. Sunday the injections of neupogen will begin again to assist in the growth of new cells. This time, however, the dosage will be less. We are grateful that during this entire process he was able to be a clinic outpatient.

~Carole

PS Of interest to us (and no one else) is that May 29 is Dr. Collins' birthday so Dr. "V" covered for him. She is a brilliant physician whose last name is longer than most can pernounce so goes by Dr. V. She has covered for Dr. Collins and seen Doug before.